Girls who failed to win the hearts of their boyfriends - "losing heroines."

One day, Kazuhiko Nukumizu, a light novel-loving, philosophical boy, happens to witness a popular girl in his class being dumped by a boy she has known since childhood. The girl who was dumped was Anna Yanami, an overindulgent childhood friend heroine. This leads to Nukumizu getting involved with Yanami at every opportunity, and his daily life gradually changes as he becomes involved with other girls with a sense of defeat, such as Lemon Yakishio, the energetic sports heroine in the track club, and Chika Komari, the shy, small animal-like heroine in the literature club.

A strange youth that Nukumizu never thought possible, somehow tangled up with Makeine - Losing Heroines, now unfolds!

A crazy, chaotic and reckless youth story that takes place around Toyohashi City, the setting for the plot.